An antacid preparation in the treatment of duodenal ulcer.
نویسنده
چکیده
R. J. EARLAM, M.A., M.CHIR., F.R.C.S. Consultant Surgeon, The London Hospital 3. T. WRIGHT, D.M., F.R.C.P. Consultant Physician, The London Hospital S. J. W. EVANS, B.A., M.B.C.S. Honorary Lecturer in Computer Science, The London Hospital P. HILLENBRAND, M.B., B.S., M.R.C.P. Consultant Physician, Good Hope General Hospital, Sutton Coldfield, West Midlands M. J. LANCASTER-SMITH, M.R.C.P. Consultant Physician, Queen Mary's Hospital, Sidcup, Kent R. H. BALME, D.M., F.R.C.P. Consultant Physician, Upton Hospital Slough, Berkshire D. E. BARNARDO, B.SC., M.D., M.R.C.P. Consultant Physician, Queen Mary's Hospital, London
منابع مشابه
Controlled therapeutic trial to determine the optimum dose of antacids in duodenal ulcer.
Antacids are widely used in the management of duodenal ulcer but the optimum dose of antacid required for ulcer healing has not been determined. We therefore studied 107 patients with endoscopically diagnosed duodenal ulcer who were allotted at random to one of the following treatment groups; placebo (group P) and antacid (groups A, B and C). A liquid antacid (Aludrox MH, Wyeth) with neutralisi...
متن کاملFactors affecting the healing rate of duodenal and pyloric ulcers with low-dose antacid treatment.
In 80 patients with duodenal ulcer, the effects of various factors--symptoms, endoscopic findings, and peak acid output (PAO)--on the healing rate were studied during eight weeks of outpatient therapy with low-dose antacid (neutralising capacity less than 50 mmol HCl/d). Fifty-six per cent of the ulcers healed. The following unfavourable factors were found to cause a significant delay in ulcer ...
متن کاملRisk factors for healing of duodenal ulcer under antacid treatment: do ulcer patients need individual treatment?
In order to identify the risk factors affecting the healing of duodenal ulcer, a clinical trial with effective dose of antacid was carried out in 53 patients. Duration of ulcer history, number of relapses, duration of the last and present relapse, number, duration and severity of pain attacks in the present ulcer relapse, pain radiation to back, vomiting, appetite, smoking habit, intake of anal...
متن کاملA Simple Mathematical Model of Gastric Neutralization of Antacid in Vivo
EDITORIAL SYNOPSIS Because all the parameters needed to calculate an adequate dose of antacid for patients with peptic ulcer will probably never be known before treatment, a mathematical method is presented of calculating the minimum dose using the data of various authors as regards gastric secretion and emptying. Also studied is the effect of antacids on secretion rate and emptying time. It wa...
متن کاملIs there a place in the United Kingdom for intensive antacid treatment for chronic peptic ulceration?
Sixty nine patients with chronic duodenal or juxtapyloric ulceration were studied in a prospective double blind randomised trial to compare the efficacy of antacid and placebo at high (30 ml seven times daily) and low (10 ml as required) doses. After four weeks ulcers had healed in 12 out of 18 patients (67%) receiving "low dose" antacid compared with in six out of 17 patients (35%) receiving l...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Practitioner
دوره 220 1316 شماره
صفحات -
تاریخ انتشار 1978